Showing posts with label Dr. Bruce Gillis. Show all posts
Showing posts with label Dr. Bruce Gillis. Show all posts

Monday, May 8, 2017

Casting Light on the Shadow of Fibromyalgia: Finding the cause


Radiating the Shadow of Light


As suggested in my article for ProHealth, there is a problem with research on fibromyalgia. It is all over the place. The reason for this is partly due to how research is funded—sad, but true.


Drug Research

Several drugs have been suggested for treating fibromyalgia  but are they helping?


The FDA *Voice of the Patient (October 2014) said:

“According to the polling, nearly all in-person and web participants reported taking or having taken a prescription medication to treat their fibromyalgia symptoms. Prescription drug therapies were described as having widely varying degrees of effectiveness, and many participants noted limited benefits or decreased benefit over time. Additionally, even if effective, many participants described that they could not sustain treatment because they were unable to tolerate their side effects.”

*A polling of FDA approved Lyrica®, Cymbalta®, Savella® and other commonly prescribed medications.

 

Also in 2014, The Cochran Library database said while it seems helpful in those who tolerate it, the number who benefit from Pregabalin (Lyrica) is very small. Only one person in ten will have any benefits. (Pregabalin for pain in fibromyalgia in adults, accessed April 29, 2017) That is underwhelming evidence compared to the reported clinical trials on which the FDA based their approval.

Getting Unstuck

In our books I write about the importance of critical thinking and problem solving, i.e. determining what we think we want or need then go about finding ways to achieve it. But, when we change the goal, or even our interpretation of the goal, so changes the way we get there. Simply masking our symptoms so we can learn to live with it isn’t a lofty goal to me. Instead, we should be looking at the cause, the necessary step to finding a cure. That said, I support any medication, treatment, or therapy you and your doctor work together to find, but we can’t get stuck in thinking that’s all there is. We need to know how to treat fibromyalgia as a disease and manage it as we do diabetes, thyroid disease, etc.

The Biology of Body Matter

I began reviewing research, commentaries, and reports on fibromyalgia in 2001 when I first started writing our book, Integrative Therapies for Fibromyalgia, Chronic Fatigue Syndrome and Myofascial Pain: The Mind-Body Connection, 2010. And, I have seen evidence in small studies and large that fibromyalgia is biological.

As years pass by, we see a recurring theme regarding the hypothalamus-pituitary-adrenal (HPA) axis involvement in fibromyalgia. And as we advance, we learn more about how this might work. You see, the HPA axis is constantly recalculating based on stress signals from the mind or body. For instance, if it receives feedback that there is an imbalance in the immune system this intricate system activates to restore order. 

Immune Cells

Behm FG, et al. found specific immune cells in FM using a specific method. That is what led to the FM/a® blood test. This finding doesn't necessarily negate previous studies on the HPA response in fibromyalgia. Instead, this and other “Peer-reviewed Medical Publications” (below), support immune system involvement in fibromyalgia, which could be upsetting the body's ability to achieve balance. When we treat the root cause in any disease, it makes the job of the HPA much easier.

Newsworthy Hope for the Future

Dynamic, well-respected scientists and medical research institutions will be collecting data from those of us who have tested positive with the FM/a® blood test. 
“We seek a potential set of explanations for why FM patients have their immunological abnormalities and that is why we have contracted with the genomic facilities at two major university medical centers(University of Illinois and UCLA) so we utilize their immense expertise and databases.” (Dr. Bruce Gillis, personal correspondence)

It’s important that you know this will “Take Time”. This is the first step to help scientists find treatment that is specific to the cause of fibromyalgia.

“Things Take Time (TTT).
Get this engraved on your watch crystal or the back of your cell phone.
The Grand Canyon started as a run-off problem.”
~Jeff Miller, PhD (My co-author)



Participation 

The FM/a® test “Campaign 250” is devoted to answering the basic three questions: Do I have it? What caused it? How do I treat it? If you would like to be one of the 250,0000 participates in this important research, you first need to have the FM/a® test. Start the process at http://fmtest.com/ and contact them if you can’t find answers to any of your questions. They are a wonderful bunch of folks. And, you can read my blog, FM/a® Blood Test – “How To” and My Results, which clearly explains my experience

In hope and healing,,Celeste

Related reading:



Following are downloadable peer-reviewed medical publications: (accessed, 2017)









"Adversity is only an obstacle if we fail to see opportunity."

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Celeste Cooper, RN
Author—Patient—Freelance Writer at Health Central & ProHealth Advocate

Celeste’s Website: http://CelesteCooper.com

Learn more about Celeste’s books at her website or find links here on Celeste's  blog. Subscribe to posts by using the information in the upper right hand corner or use the share buttons to share with others.


All blogs and comments are based on the author's opinions and are not meant to replace medical advice.  

Wednesday, April 19, 2017

EpicGenetics Announces Major Clinical Study to Locate Genetic Markers Unique to People with Fibromyalgia and Explore New Treatment Approaches



EpicGenetics, with the Assistance of Leading Medical Centers, Expands Clinical Study of FM/a® Test to Diagnose Fibromyalgia, Identify Genetic Markers Unique to the Disorder and Explore Direct Treatment Approaches

- Provides Research Gift to the Faustman Immunobiology Lab at
Massachusetts General Hospital/Harvard Medical School to
Support Research on Fibromyalgia Treatments -

In February of 2016, I wrote a blog on the importance of a well-designed study on fibromyalgia, Are Fibromyalgia Researchers on a Common Path?

In June of 2016, I wrote a blog on my personal experience with the FM/a® blood test providing a detailed guideline on how the process worked for me, and my results.

In an article that will be published soon by ProHealth, I write about the chaos surrounding concrete diagnostic criteria and the disparaging consequences.

Breaking News

And now I am excited to write about new research that could very well provide us with a true understanding of a “disease” called fibromyalgia.

I have been waiting for permission to share what you are about to read.

LOS ANGELES – April 19, 2017 – EpicGenetics, a privately held biomedical company dedicated to improving the diagnosis and treatment of fibromyalgia, today announced that it has engaged the University of California, Los Angeles (UCLA)* and the University of Illinois College of Medicine Chicago (UIC). Both university research centers will be sequencing the exomes of patients to improve the diagnosis of fibromyalgia through the application of the FM/a® Test and to allow EpicGenetics to detect fibromyalgia disease-specific gene markers. Additionally, Bruce Gillis, M.D., CEO of EpicGenetics, has made a research gift to the Immunobiology Laboratory at the Massachusetts General Hospital directed by Denise Faustman, M.D., Ph.D., to continue its robust clinical research regarding a direct treatment for fibromyalgia. 

The FM/a® Test is an FDA-compliant blood test that diagnoses fibromyalgia by identifying the presence of specific white blood cell abnormalities that have been documented to exist in these patients. The FM/a® Test accurately and objectively diagnoses this chronic disorder that afflicts millions of men, women and children.


Committment

I have been committed to understanding and educating my peers on fibromyalgia over the past two decades, but I have never been as excited as I am right now. To be part of a study that has the potential to prove fibromyalgia as a disease with definite treatments is probably the pinnacle of my work.

Dr. Gillis Is Committed

About this announcement, Dr. Gillis told me, “We are hoping to finally bring our understanding of fibromyalgia out of the Dark Ages. Millions of women, men and children suffer from fibromyalgia, yet our understanding and acknowledgement of this as a legitimate medical condition is still so limited and has not advanced in a meaningful way in decades. With the clinical efforts being initiated as part of today’s announcement, we hope to finally change this and, ultimately, we are seeking to provide answers and better solutions for people who suffer from fibromyalgia.”

Follow @TheFMTest on Facebook

What is “Campaign 250?”

According to Epicgenetics, Campaign 250 represents the largest and most ambitious study to investigate fibromyalgia’s genetic origins, as well as develop a treatment protocol addressing the underlying biology of the disease.

Download PDF at
https://drive.google.com/file/d/0B6iFloW6MyVwakttOHFGUWpRNkk/view?usp=sharing


Under contract with researchers from both UCLA* and the University of Illinois College of Medicine Chicago, Campaign 250 will conduct Whole-Exome genetic testing on up to 250,000 patients who have received a positive FM/a® fibromyalgia diagnosis. All direct testing costs will be covered by EpicGenetics**. Based upon the findings of this testing and once treatment protocols have received regulatory and institutional approvals, FM/a® Test positive patients will be invited to participate in a fibromyalgia-specific vaccine clinical trial to reverse the biology of fibromyalgia. The vaccine trial will be conducted in cooperation with The Faustman Lab and Dr. Denise Faustman at the Massachusetts General Hospital/Harvard School of Medicine, the clinical trial will seek to alleviate fibromyalgia-related symptoms…

* The David Geffen School of Medicine at UCLA has been engaged to sequence the exomes of research subjects
**The genetic tests will require a $45 administration fee to cover the processing of the test, which is a $2,500+ cost being provided at no charge. 

Participation

I am anxious to see if I carry the fibromyalgia gene and I am honored to participate in providing information that can make a difference in the lives of people all over the world who live with fibromyalgia. I hope you can join me on this next chapter.




“The mighty oak was once a little nut that stood its ground.”
--Unknown


Additional Information:
FM/a® Blood Test – “How To” – My detailed account of the process


(Signature line appended July 2018)



In healing,

Celeste Cooper, RN / Author, Freelancer, Advocate

Think adversity?-See opportunity!



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Learn more about Celeste’s books here. Subscribe to posts by using the information in the upper right hand corner or use the share buttons to share with others. 

Celeste's Website

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